Bupropion PR 75mg (prolonged-release) is an oral antidepressant primarily prescribed for depression and can also be used in the treatment of smoking addiction and seasonal affective disorder. As a norepinephrine and dopamine reuptake inhibitor, it works by increasing the levels of certain chemical messengers in the brain, which helps regulate mood and decrease cravings in smoking cessation. Bupropion PR tablets should be swallowed whole and are available in several brand names such as Wellbutrin, Zyban, and various generics. The medication is believed to offer fewer side effects compared to other antidepressants, and its use should be closely monitored for any sudden changes in mood or behavior.