Orlistat 120mg capsules are used with a reduced‑calorie, low‑fat diet to help adults with overweight or obesity lose weight and maintain weight loss by blocking gastrointestinal lipases so about one‑third of dietary fat isn’t absorbed and is excreted in stool. The usual dose is 120mg three times daily during or within 1 hour after each main meal that contains fat; skip the dose if the meal is missed or fat‑free. A daily multivitamin (A, D, E, K, beta‑carotene) should be taken at a different time due to reduced absorption. Common effects include oily stools, urgency, and more frequent bowel movements.